water treatment chemicals pdf
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The biological relevance of DMClU primarily stems from its potential as an antineoplastic agent. Similar to other uracil analogs, DMClU can interfere with nucleic acid synthesis by mimicking natural nucleobases. This interference can disrupt the replication of cancer cells, making DMClU a candidate for further exploration in cancer treatment protocols. Studies have shown that compounds with modified uracil structures can exhibit selective toxicity toward cancerous cells while sparing normal cells, a feature that is extremely valuable for chemotherapy.
1,3-dimethyl-6-chlorouracil...
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One of the significant aspects of 6-chloro-3-methyluracil is its potential role as an antitumor agent. Research has indicated that certain uracil derivatives can interfere with nucleic acid metabolism, potentially leading to apoptosis in cancer cells. The mechanism of action typically involves the incorporation of these analogs into RNA or DNA, disrupting normal cellular processes. The chlorinated variant may have enhanced efficacy due to the electron-withdrawing nature of chlorine, which could influence the compound's ability to mimic natural nucleotides in vivo.
6 chloro 3 methyl uracil...